Non-exercise estimation of peak oxygen uptake in patients with ischaemic heart disease and heart failure using seismocardiography
Executive Summary
This study evaluated the accuracy of a novel seismocardiography (SCG)-based equation (SCG 4.7_HD) for estimating peak oxygen uptake (VO2peak) in patients with ischemic heart disease (IHD) and heart failure with reduced ejection fraction (HFrEF). The SCG-based method was compared to the gold-standard cardiopulmonary exercise test (CPET) and showed poor-to-moderate agreement with significant overestimation and large estimation errors. Furthermore, the SCG method failed to detect changes in VO2peak following 12 weeks of cardiac rehabilitation, limiting its clinical applicability.
Answer Machine Insights
Q: How accurate was the SCG 4.7_HD in estimating VO2peak compared to CPET?
The SCG 4.7_HD showed poor-to-moderate agreement with CPET, overestimating VO2peak by 2.1 mL/min/kg and having a MAPE of 29.1%.
The SCG 4.7_HD overestimated VO2peak (2.1 mL min−1 kg−1, P = 0.003) with 95% limits of agreement ranging ±10.9 mL min−1 kg−1 when compared with CPET.
Q: Was the SCG method able to detect changes in VO2peak after cardiac rehabilitation?
No, the SCG method failed to detect changes in VO2peak following 12 weeks of cardiac rehabilitation.
No correlation was observed between delta SCG 4.7_HD and CPET after CR for patients with HFrEF.
Key Results
The SCG 4.7_HD overestimated VO2peak by 2.1 mL/min/kg with 95% limits of agreement ranging ±10.9 mL/min/kg compared to CPET.
The mean absolute percentage error (MAPE) of the SCG method was 29.1%, exceeding the predefined clinical relevance threshold of 10%.
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Evidence Rating
Relevance
high Priority